Manual article review is required for this article
Manual article review is required for this article
Manual article review is required for this article
Our results spotlight the potential for exploiting TOP1 inhibition to be combined with CX-5461 like a non-genotoxic tactic in targeting HR-proficient HGSC.This is significant due to the fact present clinically accredited chemotherapeutics have perfectly-documented off-focus on interactions with TOP2B, that have Beforehand been shown to lead to both